| ชื่อเรื่อง | : | Developing a nontypeable Haemophilus influenzae (NTHi) vaccine |
| นักวิจัย | : | Poolman, Jan Theunis. , Bakaletz, Lauren O. , Cripps, Allan W. , Denoel, Philippe A. , Forsgren, Arne. , Kyd, Jennelle M. , Lobet, Yves. |
| คำค้น | : | Vaccines , TBA. , 920109 Infectious Diseases. , 110309 Infectious Diseases. , Communicable diseases. , Haemophilus influenzae. , Otitis media. , NTHi (or nontypable Haemophilus influenzae) -- Animal models -- Otitis -- LPD -- LB1-fimbrin-P5 -- OMP26 -- Vaccine research |
| หน่วยงาน | : | Central Queensland University, Australia |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2544 |
| อ้างอิง | : | http://hdl.cqu.edu.au/10018/58495 |
| ที่มา | : | Poolman, JT, Bakaletz, L, Cripps, A, Denoel, PA, Forsgren, A, Kyd, J & Lobet, Y 2000, 'Developing a nontypeable Haemophilus influenzae (NTHi) vaccine', Vaccine, vol. 19, Supp. 1, pp. S108-S115, http://dx.doi.org/10.1016/S0264-410X(00)00288-7 |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | Vaccine. United Kingdom : Elsevier Ltd, 2001. Vol. 19, (2001), p. S108-S115 8 pages Refereed 0264-410X 1873-2518 (online) , ACQUIRE [electronic resource] : Central Queensland University Institutional Repository. |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | There is a current high demand for nontypable Haemophilus influenzae (NTHi) vaccines. Various options for the composition of such vaccines are possible. Decisions about the vaccine composition have to take into account the antigenic variability of NTHi, so even complex immunogens such as whole bacteria would preferentially have a tailor-made antigenic composition. We will present a summary of NTHi vaccine development, describing research efforts from SmithKline Beecham and other laboratories. Currently, major (P1, P2, P4, P5) and minor (P6, D15, TbpA/B, …) outer membrane proteins, LPS, adhesins (HMW, Hia, pili, P5) are being studied. Preclinical results with LPD, P5 (LB1) and OMP26 from our laboratories will be described including the use of animal models of otitis and lung infection. |
| บรรณานุกรม | : |
Poolman, Jan Theunis. , Bakaletz, Lauren O. , Cripps, Allan W. , Denoel, Philippe A. , Forsgren, Arne. , Kyd, Jennelle M. , Lobet, Yves. . (2544). Developing a nontypeable Haemophilus influenzae (NTHi) vaccine.
กรุงเทพมหานคร : Central Queensland University, Australia. Poolman, Jan Theunis. , Bakaletz, Lauren O. , Cripps, Allan W. , Denoel, Philippe A. , Forsgren, Arne. , Kyd, Jennelle M. , Lobet, Yves. . 2544. "Developing a nontypeable Haemophilus influenzae (NTHi) vaccine".
กรุงเทพมหานคร : Central Queensland University, Australia. Poolman, Jan Theunis. , Bakaletz, Lauren O. , Cripps, Allan W. , Denoel, Philippe A. , Forsgren, Arne. , Kyd, Jennelle M. , Lobet, Yves. . "Developing a nontypeable Haemophilus influenzae (NTHi) vaccine."
กรุงเทพมหานคร : Central Queensland University, Australia, 2544. Print. Poolman, Jan Theunis. , Bakaletz, Lauren O. , Cripps, Allan W. , Denoel, Philippe A. , Forsgren, Arne. , Kyd, Jennelle M. , Lobet, Yves. . Developing a nontypeable Haemophilus influenzae (NTHi) vaccine. กรุงเทพมหานคร : Central Queensland University, Australia; 2544.
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