| ชื่อเรื่อง | : | Optimisation of oral immunization through receptor-mediated targeting of M cells |
| นักวิจัย | : | Foxwell, A. Ruth. , Cripps, Allan W. , Kyd, Jennelle M. |
| คำค้น | : | Not a CQU Research Flagship , Immunization. , Oral vaccines. , Drug receptors. , 730102 Immune system and allergy , 320202 Cellular Immunology , Oral immunization -- Vaccines -- M-cells -- Receptor-targeting -- PAMP -- PRR |
| หน่วยงาน | : | Central Queensland University, Australia |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2550 |
| อ้างอิง | : | http://hdl.cqu.edu.au/10018/12845 , http://acquire.cqu.edu.au:8080/vital/access/manager/Repository/cqu:2832 , cqu:2832 |
| ที่มา | : | Foxwell, A R, Cripps, A W & Kyd, J M 2007, 'Optimisation of oral immunization through receptor-mediated targeting of M cells', Human Vaccines, vol. 3, no. 5, pp. 220-223. |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | Human vaccines Newton, MA. : Landes Bioscience, 2007. Vol. 3, no. 5 (Sep.-Oct, 2007), p. 220-223 4 pages Refereed 1554-8600 1554-8619 (online) , aCQUIRe [electronic resource] : Central Queensland University Institutional Repository. |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | Only a small number of oral vaccines are available for routine immunizations despite a significant research effort and a number of obvious advantages over parenteral vaccination. The major roadblock in the development of oral vaccines has been mostly attributed to a lack of ability to specifically target antigen to the mucosal immune system of the gastrointestinal tract. This commentary examines the accessing of M cells through receptor interaction on the apical surface of the cell in order to enhance the efficiency and efficacy of oral immunization. Three challenges have been identified (1) the availability of appropriate experimental models to study M cell targeting and transcytosis; (2) appropriate tools for investigating the specificity of targeting; (3) the identification of priority targets on the apical surface of M cells. |
| บรรณานุกรม | : |
Foxwell, A. Ruth. , Cripps, Allan W. , Kyd, Jennelle M. . (2550). Optimisation of oral immunization through receptor-mediated targeting of M cells.
กรุงเทพมหานคร : Central Queensland University, Australia. Foxwell, A. Ruth. , Cripps, Allan W. , Kyd, Jennelle M. . 2550. "Optimisation of oral immunization through receptor-mediated targeting of M cells".
กรุงเทพมหานคร : Central Queensland University, Australia. Foxwell, A. Ruth. , Cripps, Allan W. , Kyd, Jennelle M. . "Optimisation of oral immunization through receptor-mediated targeting of M cells."
กรุงเทพมหานคร : Central Queensland University, Australia, 2550. Print. Foxwell, A. Ruth. , Cripps, Allan W. , Kyd, Jennelle M. . Optimisation of oral immunization through receptor-mediated targeting of M cells. กรุงเทพมหานคร : Central Queensland University, Australia; 2550.
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