| ชื่อเรื่อง | : | Synthesis of bis-peptides attached on poly[n]norbornene molecular scaffolds with well-defined relative positions and distances |
| นักวิจัย | : | Shang Muhong. , Warrener, Ronald Norman. , Butler, Douglas N. , Murata, Yasujiro. , Margetic, Davor. |
| คำค้น | : | Peptides , Cyclobutane. , Ring formation (Chemistry) , Peptides -- Cycloaddition reactions -- Polycycles -- Peptidomimetics -- Norbornene |
| หน่วยงาน | : | Central Queensland University, Australia |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2553 |
| อ้างอิง | : | http://hdl.cqu.edu.au/10018/58343 |
| ที่มา | : | Shang, M, Warrener, R N, Butler, D N, Murata, Y & Margetić, D 2011, 'Synthesis of bis-peptides attached on poly[n]norbornene molecular scaffolds with well-defined relative positions and distances', Molecular Diversity, Vol. 15, no. 2, pp. 541-560, http://dx.doi.org/10.1007/s11030-010-9279-9 |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | Molecular diversity. Netherlands : Springer Science+Business Media, 2010. Vol. 15, no. 2 (2010), p. 541-560 20 pages Refereed 1381-1991 , |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | This article describes novel synthetic approaches to polynorbornene molecular scaffolds substituted with peptides at various, well-defined positions. A library of norbornene building blocks with attached peptides was prepared. Alkene cyclobutane epoxide (ACE) coupling method was used as a key step reaction for the connection of two norbornene building blocks into bis-peptide scaffolds. Photodimerization of cyclobutene diesters offers an alternative route to polynorbornene bis-peptides. Pyrrolo-peptides were used for preparation of peptide-substituted 7-aza norbornenes. Asymmetrical bis-peptide scaffolds were prepared by ACE coupling of peptide-norbornane epoxide with another norbornene-peptide block. Chemical elaboration of bridgehead dimethyl esters of ACE products or epoxide ACE reagents was also used for peptide attachment. |
| บรรณานุกรม | : |
Shang Muhong. , Warrener, Ronald Norman. , Butler, Douglas N. , Murata, Yasujiro. , Margetic, Davor. . (2553). Synthesis of bis-peptides attached on poly[n]norbornene molecular scaffolds with well-defined relative positions and distances.
กรุงเทพมหานคร : Central Queensland University, Australia. Shang Muhong. , Warrener, Ronald Norman. , Butler, Douglas N. , Murata, Yasujiro. , Margetic, Davor. . 2553. "Synthesis of bis-peptides attached on poly[n]norbornene molecular scaffolds with well-defined relative positions and distances".
กรุงเทพมหานคร : Central Queensland University, Australia. Shang Muhong. , Warrener, Ronald Norman. , Butler, Douglas N. , Murata, Yasujiro. , Margetic, Davor. . "Synthesis of bis-peptides attached on poly[n]norbornene molecular scaffolds with well-defined relative positions and distances."
กรุงเทพมหานคร : Central Queensland University, Australia, 2553. Print. Shang Muhong. , Warrener, Ronald Norman. , Butler, Douglas N. , Murata, Yasujiro. , Margetic, Davor. . Synthesis of bis-peptides attached on poly[n]norbornene molecular scaffolds with well-defined relative positions and distances. กรุงเทพมหานคร : Central Queensland University, Australia; 2553.
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