The use of a multimedia program as a teaching tool, especially for special needs students, offers sufficient and personal attention to the student using it, while allowing instruction to proceed at the student's pace and also supporting in motivation. The purposes of this proposal are (1) to examine the degree of effectiveness of a multimedia support system in teaching/learning, in comparison with the traditional print-based learning method for special needs students, and (2) to discover more about the qualitative aspects of learning using multimedia technology. An experimental multimedia program Life: Bone Numbing! was designed and developed based on discussions with teachers of students with deafness in Thailand. In this proposal, the author will propose details to design of at least three Empirical Studies of students with deafness in Thailand who are learning American Finger Spelling. From the Preliminary Study, evidence indicates that multimedia learning promises to be as effective as the traditional print-based method in teaching/learning. This finding indicates that a multimedia system could replace the teacher for some forms of learning, such as finger spelling. This could be very valuable in Thailand because there are insufficient teachers for the students with deafness who need to learn American Finger Spelling.