Transport of hazardous waste places community and surrounding environment at risk, especially people who spend their time near roads commonly routed by truck take the greatest risk. The selection of route for transporting hazardous waste is therefore an important aspect to reduce the community at risk. Traditionally, a shortest route is a prefer choice in route selection, but it often consists of urban area that can place community in harm situation. The concept of sustainability can broader the goal of hazardous waste transport that economic issues should not be solely considered as a major factor in hazardous waste transport, social welfare in term of safety and environmental risk should be concerned and incorporated into every stages of the decision making process. This paper provides a holistic framework of decision making process based on the sustainability paradigm for hazardous waste transport by incorporating factors and criteria in line with economic, environment and social dimension. Using Geographic Information System (GIS) to manage and organize complex data sources and then derive weight and score via Multi Criteria Decision Analysis (MCDA) for the evaluation of risk involved. The proposed hazardous conceptual model can be very helpful to carriers and to governmental policy-makers when attempting to evaluate possible routes for transport hazardous waste.