| ชื่อเรื่อง | : | Detecting Recombination in 4-Taxa DNA Sequence Alignments with Bayesian Hidden Markov Models and Markov Chain Monte Carlo |
| นักวิจัย | : | McGuire, Graine , Husmeier, Dirk |
| คำค้น | : | - |
| หน่วยงาน | : | Edinburgh Research Archive, United Kingdom |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2546 |
| อ้างอิง | : | McGuire Graine (External), Husmeier, DH. (2003-01-01) Detecting Recombination in 4-Taxa DNA Sequence Alignments with Bayesian Hidden Markov Models and Markov Chain Monte Carlo, Molecular Biology and Evolution 20 (3) 315-337 , 0737-4038 , http://mbe.oxfordjournals.org/cgi/content/abstract/20/3/315 , 10.1093/molbev/msg039 , http://hdl.handle.net/1842/2570 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | - |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | This article presents a statistical method for detecting recombination in DNA sequence alignments, which is based on combining two probabilistic graphical models: (1) a taxon graph (phylogenetic tree) representing the relationship between the taxa, and (2) a site graph (hidden Markov model) representing interactions between different sites in the DNA sequence alignments. We adopt a Bayesian approach and sample the parameters of the model from the posterior distribution with Markov chain Monte Carlo, using a Metropolis-Hastings and Gibbs-within-Gibbs scheme. The proposed method is tested on various synthetic and real-world DNA sequence alignments, and we compare its performance with the established detection methods RECPARS, PLATO, and TOPAL, as well as with two alternative parameter estimation schemes. |
| บรรณานุกรม | : |
McGuire, Graine , Husmeier, Dirk . (2546). Detecting Recombination in 4-Taxa DNA Sequence Alignments with Bayesian Hidden Markov Models and Markov Chain Monte Carlo.
กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom . McGuire, Graine , Husmeier, Dirk . 2546. "Detecting Recombination in 4-Taxa DNA Sequence Alignments with Bayesian Hidden Markov Models and Markov Chain Monte Carlo".
กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom . McGuire, Graine , Husmeier, Dirk . "Detecting Recombination in 4-Taxa DNA Sequence Alignments with Bayesian Hidden Markov Models and Markov Chain Monte Carlo."
กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom , 2546. Print. McGuire, Graine , Husmeier, Dirk . Detecting Recombination in 4-Taxa DNA Sequence Alignments with Bayesian Hidden Markov Models and Markov Chain Monte Carlo. กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom ; 2546.
|
ridm@nrct.go.th ระบบคลังข้อมูลงานวิจัยไทย รายการโปรดที่คุณเลือกไว้
