| ชื่อเรื่อง | : | Iron-catalyzed directed C2-alkylation and alkenylation of indole with vinylarenes and alkynes |
| นักวิจัย | : | Wong, Mun Yee , Yamakawa, Takeshi , Yoshikai, Naohiko |
| คำค้น | : | DRNTU::Science::Chemistry::Organic chemistry::Heterocyclic compounds |
| หน่วยงาน | : | Nanyang Technological University, Singapore |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2558 |
| อ้างอิง | : | Wong, M. Y., Yamakawa, T., & Yoshikai, N. (2015). Iron-catalyzed directed C2-alkylation and alkenylation of indole with vinylarenes and alkynes. Organic letters, 17(3), 442-445. , http://hdl.handle.net/10220/25309 , http://dx.doi.org/10.1021/ol503395g |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | Organic letters |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | An iron–N-heterocyclic carbene catalyst generated from an iron(III) salt, an imidazolinium salt, and a Grignard reagent promotes alkylation and alkenylation reactions at the indole C2-position with vinylarenes and internal alkynes, respectively, via imine-directed C–H activation. The former reaction affords 1,1-diarylalkane derivatives with exclusive regioselectivity. Deuterium-labeling experiments suggest that these reactions involve oxidative addition of the C–H bond to the iron center, insertion of the unsaturated bond into the Fe–H bond, and C–C reductive elimination. NRF (Natl Research Foundation, S’pore) |
| บรรณานุกรม | : |
Wong, Mun Yee , Yamakawa, Takeshi , Yoshikai, Naohiko . (2558). Iron-catalyzed directed C2-alkylation and alkenylation of indole with vinylarenes and alkynes.
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Wong, Mun Yee , Yamakawa, Takeshi , Yoshikai, Naohiko . 2558. "Iron-catalyzed directed C2-alkylation and alkenylation of indole with vinylarenes and alkynes".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Wong, Mun Yee , Yamakawa, Takeshi , Yoshikai, Naohiko . "Iron-catalyzed directed C2-alkylation and alkenylation of indole with vinylarenes and alkynes."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2558. Print. Wong, Mun Yee , Yamakawa, Takeshi , Yoshikai, Naohiko . Iron-catalyzed directed C2-alkylation and alkenylation of indole with vinylarenes and alkynes. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2558.
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