Institutional buildings contain different types of functional spaces which require different types of heating, ventilating and air conditioning (HVAC) systems. In addition, institutional buildings should be designed to maintain an optimal indoor comfort condition with minimal energy consumption and minimal negative environmental impact. Recently there has been a significant interest in implementing desiccant cooling technologies within institutional buildings. Solar desiccant cooling systems are reliable in performance, environmentally friendly and capable of improving indoor air quality at a lower cost. In this study, a solar desiccant cooling system for an institutional building in subtropical Queensland (Australia) is assessed using TRNSYS 16 software. This system has been designed and installed at the Rockhampton campus of Central Queensland University. The system's technical performance, economic analysis, energy savings, and avoided gas emission are quantified in reference to a conventional HVAC system under the influence of Rockhampton's typical meteorological year. The technical and economic parameters that are used to assess the system's viability are: coefficient of performance (COP), solar fraction, life cycle analysis, payback period, present worth factor and the avoided gas emission. Results showed that, the installed cooling system at Central Queensland University which consists of 10m 2 of solar collectors and a 0.400m 3 of hot water storage tank, achieved a 0.7 COP and 22% of solar fraction during the cooling season. These values can be boosted to 1.2 COP and 69% respectively if 20m 2 of evacuated tube collector's area and 1.5m 3 of solar hot water storage volume are installed.