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Molecular identification of interleukin-2 in the lymphoid tissues of the common brushtail possum, Trichosurus vulpecula

หน่วยงาน Central Queensland University, Australia

รายละเอียด

ชื่อเรื่อง : Molecular identification of interleukin-2 in the lymphoid tissues of the common brushtail possum, Trichosurus vulpecula
นักวิจัย : Young, Lauren J. , Cross, M. L. , Duckworth, Janine A. , Flenady, Sabine. , Belov, Katherine.
คำค้น : Trichosurus vulpecula , Pure basic research. , 920108 Immune System and Allergy. , 070705 Veterinary Immunology. , Veterinary immunology. , Marsupials , Brushtail possum -- Cytokine -- Interleukin-2 -- Marsupial -- Trichosurus vulpecula
หน่วยงาน : Central Queensland University, Australia
ผู้ร่วมงาน : -
ปีพิมพ์ : 2555
อ้างอิง : http://hdl.cqu.edu.au/10018/922822
ที่มา : Young, L, Cross, M, Duckworth, J, Flenady, S & Belov, K 2012, 'Molecular identification of interleukin-2 in the lymphoid tissues of the common brushtail possum, Trichosurus vulpecula', Developmental & Comparative Immunology, vol. 36, no. 1 , pp.236-240, http://dx.doi.org/10.1016/j.dci.2011.05.010
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Developmental & comparative immunology. UK : Pergamon, 2012. Vol. 36, no. 1 (2012), p. 236-240 5 pages Refereed 0145-305X 1879-0089 (online) , ACQUIRE [electronic resource] : Central Queensland University Institutional Repository.
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

The common brushtail possum (Trichosurus vulpecula) is an Australian marsupial. Here we describe the identification of possum interleukin-2 in mitogen-stimulated lymph node cells. We used a strategy of Rapid amplification of cDNA ends using probes designed from recently-sequenced marsupial genomes to identify the IL2 gene and then confirmed that IL-2 expression in possum immune tissue occurs in a similar manner to that in their eutherian counterparts. The predictive possum IL-2 peptide showed 28% and 35% amino acid sequence homology with the mouse and human IL-2 molecules, respectively, consistent with the divergence found within this cytokine family. Despite this low sequence identity, possum IL-2 still possessed the characteristic hallmarks of mammalian IL-2, such as a predicted signal peptide and conserved family motifs.

บรรณานุกรม :
Young, Lauren J. , Cross, M. L. , Duckworth, Janine A. , Flenady, Sabine. , Belov, Katherine. . (2555). Molecular identification of interleukin-2 in the lymphoid tissues of the common brushtail possum, Trichosurus vulpecula.
    กรุงเทพมหานคร : Central Queensland University, Australia.
Young, Lauren J. , Cross, M. L. , Duckworth, Janine A. , Flenady, Sabine. , Belov, Katherine. . 2555. "Molecular identification of interleukin-2 in the lymphoid tissues of the common brushtail possum, Trichosurus vulpecula".
    กรุงเทพมหานคร : Central Queensland University, Australia.
Young, Lauren J. , Cross, M. L. , Duckworth, Janine A. , Flenady, Sabine. , Belov, Katherine. . "Molecular identification of interleukin-2 in the lymphoid tissues of the common brushtail possum, Trichosurus vulpecula."
    กรุงเทพมหานคร : Central Queensland University, Australia, 2555. Print.
Young, Lauren J. , Cross, M. L. , Duckworth, Janine A. , Flenady, Sabine. , Belov, Katherine. . Molecular identification of interleukin-2 in the lymphoid tissues of the common brushtail possum, Trichosurus vulpecula. กรุงเทพมหานคร : Central Queensland University, Australia; 2555.