Close examination of epidemiological data reveals burdens of disease particular to culturally and linguistically diverse (CALD) migrants as these individuals adjust to both culture and modernisation gaps. Despite the increased risk of hypertension, diabetes, overweight/obesity, and CVD, individuals from CALD groups are less likely to be proactive in accessing health care or undertaking preventative measures to ensure optimal health outcomes. The purpose of this paper is to review literature which outlines the barriers, challenges, and enablers of physical activity in CALD groups who have recently migrated to Western society, and to identify key strategies to increase physical activity participation for these individuals. Electronic and manual literature searches were used to identify 57 publications which met the inclusion criteria. Findings from the review indicate that migration to western societies has a detrimental effect on the health status and health behaviours of CALD groups as they assimilate to their new surroundings, explore different cultures and customs, and embrace a new way of life. In particular, there is evidence that physical inactivity is common in migrant CALD groups, and is a key contributing risk factor to chronic disease for these individuals. Challenges and barriers that limit physical activity participation in CALD groups include; cultural and religious beliefs, issues with social relationships, socio-economic challenges, environmental barriers, and perceptions of health and injury. Strategies that may assist with overcoming these challenges and barriers consist of the need for cultural sensitivity, the provision of education sessions addressing health behaviours, encouraging participation of individuals from the same culture, exploration of employment situational variables, and the implementation of ‘Health Action Zones’ in CALD communities. This information will inform and support the development of culturally appropriate programs designed to positively influence the physical activity behaviours of individuals from CALD populations.