Rapid prototyping (RP) is a relatively new technology that additively builds three dimensional parts layer by layer. This approach allows the complex physical structures to be fabricated rapidly and accurately using graphical data in computer. These benefits place RP technology in use by many industries for concept modeling, fit & function trial and even small-scale manufacturing. RP has also been utilized in medical applications as visuallization and modeling tools to aid with pre-or per-operative planning and production of patient models or implants. In the case of implant production, this technology allows the construction of complex three dimensional biomaterials with a predefined pattern with controlled feature size and geometry without the need for subsequent machining. Starting from the digital data of patients acquired from medical imaging system such as CT or MRI, the medical models can be fabricated easily and accurately in short times by RP technology. This paper reviews the current techniques and applications in medical areas worldwide and also highlighting the related works which are carried out in Thailand.