Objective: To determine the major-complication rate of gynecological laparoscopy in Police General Hospital. Material and Method: A retrospective and descriptive analysis of medical records from 423 women who underwent gynecological laparoscopy in Police General Hospital was conducted. Results: Four hundred twenty three women were recruited between January 2007 and December 2010. One-third of subjects had history of previous gynecological surgery. Major complication rate was 2.84% (12/423). Urinary bladder, ureter, bowel, and vesico-vaginal fistula injury were 0.95% (4), 0.71% (3), 0.95% (4), and 0.23% (1), respectively. The conversion rate to exploratory laparotomy was 4.7% (20). There was no death in subject who had serious complication in this study. The operative time trended to decline in minor operation but not changed in major and advanced operation. Two-third of major complication was intraoperative diagnosed and repaired. Conclusion: The major complication rate was 2.84%. The urologic and bowel injury are the common complications.