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A contact-imaging based microfluidic cytometer with machine-learning for single-frame super-resolution processing

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : A contact-imaging based microfluidic cytometer with machine-learning for single-frame super-resolution processing
นักวิจัย : Huang, Xiwei , Guo, Jinhong , Wang, Xiaolong , Yan, Mei , Kang, Yuejun , Yu, Hao
คำค้น : DRNTU::Engineering::Chemical engineering::Biochemical engineering
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : Kreplak, Laurent
ปีพิมพ์ : 2557
อ้างอิง : Huang, X., Guo, J., Wang, X., Yan, M., Kang, Y., & Yu, H. (2014). A Contact-Imaging Based Microfluidic Cytometer with Machine-Learning for Single-Frame Super-Resolution Processing. PLoS ONE, 9(8), e104539-. , 1932-6203 , http://hdl.handle.net/10220/20408 , http://dx.doi.org/10.1371/journal.pone.0104539
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : PLoS one
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Lensless microfluidic imaging with super-resolution processing has become a promising solution to miniaturize the conventional flow cytometer for point-of-care applications. The previous multi-frame super-resolution processing system can improve resolution but has limited cell flow rate and hence low throughput when capturing multiple subpixel-shifted cell images. This paper introduces a single-frame super-resolution processing with on-line machine-learning for contact images of cells. A corresponding contact-imaging based microfluidic cytometer prototype is demonstrated for cell recognition and counting. Compared with commercial flow cytometer, less than 8% error is observed for absolute number of microbeads; and 0.10 coefficient of variation is observed for cell-ratio of mixed RBC and HepG2 cells in solution.

บรรณานุกรม :
Huang, Xiwei , Guo, Jinhong , Wang, Xiaolong , Yan, Mei , Kang, Yuejun , Yu, Hao . (2557). A contact-imaging based microfluidic cytometer with machine-learning for single-frame super-resolution processing.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Huang, Xiwei , Guo, Jinhong , Wang, Xiaolong , Yan, Mei , Kang, Yuejun , Yu, Hao . 2557. "A contact-imaging based microfluidic cytometer with machine-learning for single-frame super-resolution processing".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Huang, Xiwei , Guo, Jinhong , Wang, Xiaolong , Yan, Mei , Kang, Yuejun , Yu, Hao . "A contact-imaging based microfluidic cytometer with machine-learning for single-frame super-resolution processing."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2557. Print.
Huang, Xiwei , Guo, Jinhong , Wang, Xiaolong , Yan, Mei , Kang, Yuejun , Yu, Hao . A contact-imaging based microfluidic cytometer with machine-learning for single-frame super-resolution processing. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2557.