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MicroRNAs : the next generation therapeutic targets in human diseases

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : MicroRNAs : the next generation therapeutic targets in human diseases
นักวิจัย : Srinivasan, Sakthivel , Selvan, Subramanian Tamil , Archunan, Govindaraju , Gulyas, Balazs , Padmanabhan, Parasuraman
คำค้น : DRNTU::Science::Medicine
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2556
อ้างอิง : Srinivasan, S., Selvan, S. T., Archunan, G., Gulyas, B., & Padmanabhan, P. (2013). MicroRNAs -the Next Generation Therapeutic Targets in Human Diseases. Theranostics, 3(12), 930-942. , 1838-7640 , http://hdl.handle.net/10220/19283 , http://dx.doi.org/10.7150/thno.7026
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Theranostics
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

MicroRNAs (miRNAs), an abundant class of ~22-nucleotide non-coding RNAs, regulate the expression of genes at post transcriptional level. MiRNAs are important regulators of eukaryotic gene expression and therefore implicated in a wide range of biological processes. The miRNA- related genetic alterations are possibly more implicated human diseases than currently appreciated. Genetic variants in miRNA target sites, called miRNA genes are identified to be associated with human diseases. This review discusses about the role of micro-RNA genes in various human diseases such as neurodegenerative disorders, cardio-vascular diseases, and metabolic disorders, and how they can be targeted as a new therapeutic tool in future with reference to drug discoveries/ development.

บรรณานุกรม :
Srinivasan, Sakthivel , Selvan, Subramanian Tamil , Archunan, Govindaraju , Gulyas, Balazs , Padmanabhan, Parasuraman . (2556). MicroRNAs : the next generation therapeutic targets in human diseases.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Srinivasan, Sakthivel , Selvan, Subramanian Tamil , Archunan, Govindaraju , Gulyas, Balazs , Padmanabhan, Parasuraman . 2556. "MicroRNAs : the next generation therapeutic targets in human diseases".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Srinivasan, Sakthivel , Selvan, Subramanian Tamil , Archunan, Govindaraju , Gulyas, Balazs , Padmanabhan, Parasuraman . "MicroRNAs : the next generation therapeutic targets in human diseases."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2556. Print.
Srinivasan, Sakthivel , Selvan, Subramanian Tamil , Archunan, Govindaraju , Gulyas, Balazs , Padmanabhan, Parasuraman . MicroRNAs : the next generation therapeutic targets in human diseases. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2556.