| ชื่อเรื่อง | : | Electrochemical amplification strategies in DNA nanosensors |
| นักวิจัย | : | Rai, Varun , Toh, Chee-Seng |
| คำค้น | : | DRNTU::Science::Chemistry::Analytical chemistry::Nucleic acids. |
| หน่วยงาน | : | Nanyang Technological University, Singapore |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2556 |
| อ้างอิง | : | Rai, V., & Toh, C.-S. (2013). Electrochemical amplification strategies in DNA nanosensors. Nanoscience and Nanotechnology Letters, 5(6), 613-623. , http://hdl.handle.net/10220/18999 , http://dx.doi.org/10.1166/nnl.2013.1633 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | Nanoscience and nanotechnology letters |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | Electrochemical DNA nanosensors exploit the intrinsic property of ssDNA to hybridize to its complementary sequence and this selective hybridization event can be translated into detectable electrochemical signals following electrochemical amplification. This review describes some of the advanced electrochemical signal amplification strategies in DNA detection relying on specific sequence hybridization with focus on electro-active intercalating reagents, primary and secondary reporter DNA probes and 'de-amplification' of signals derived from nanopores and nanochannels. These amplification strategies elegantly achieve extremely low detection limits of pico- to femtomolarity concentration and zeptomolar amount of DNAs and high specificity responses without the use of multi-step polymerase chain reaction (PCR) procedures or high sensitivity instrumentation. |
| บรรณานุกรม | : |
Rai, Varun , Toh, Chee-Seng . (2556). Electrochemical amplification strategies in DNA nanosensors.
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Rai, Varun , Toh, Chee-Seng . 2556. "Electrochemical amplification strategies in DNA nanosensors".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Rai, Varun , Toh, Chee-Seng . "Electrochemical amplification strategies in DNA nanosensors."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2556. Print. Rai, Varun , Toh, Chee-Seng . Electrochemical amplification strategies in DNA nanosensors. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2556.
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