| ชื่อเรื่อง | : | The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle |
| นักวิจัย | : | Arnaudo, Nadia , Fernández, Israel S. , McLaughlin, Stephen H. , Peak-Chew, Sew Y. , Rhodes, Daniela , Martino, Fabrizio |
| คำค้น | : | DRNTU::Science::Biological sciences::Molecular biology |
| หน่วยงาน | : | Nanyang Technological University, Singapore |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2556 |
| อ้างอิง | : | Arnaudo, N., Fernández, I. S., McLaughlin, S. H., Peak-Chew, S. Y., Rhodes, D., & Martino, F. (2013). The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle. Nature structural & molecular biology, 20(9), 1119-1121. , http://hdl.handle.net/10220/17646 , http://dx.doi.org/10.1038/nsmb.2641 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | Nature structural & molecular biology |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | The N-terminal acetylation of Sir3 is essential for heterochromatin establishment and maintenance in yeast, but its mechanism of action is unknown. The crystal structure of the N-terminally acetylated BAH domain of Saccharomyces cerevisiae Sir3 bound to the nucleosome core particle reveals that the N-terminal acetylation stabilizes the interaction of Sir3 with the nucleosome. Additionally, we present a new method for the production of protein–nucleosome complexes for structural analysis. |
| บรรณานุกรม | : |
Arnaudo, Nadia , Fernández, Israel S. , McLaughlin, Stephen H. , Peak-Chew, Sew Y. , Rhodes, Daniela , Martino, Fabrizio . (2556). The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle.
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Arnaudo, Nadia , Fernández, Israel S. , McLaughlin, Stephen H. , Peak-Chew, Sew Y. , Rhodes, Daniela , Martino, Fabrizio . 2556. "The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Arnaudo, Nadia , Fernández, Israel S. , McLaughlin, Stephen H. , Peak-Chew, Sew Y. , Rhodes, Daniela , Martino, Fabrizio . "The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2556. Print. Arnaudo, Nadia , Fernández, Israel S. , McLaughlin, Stephen H. , Peak-Chew, Sew Y. , Rhodes, Daniela , Martino, Fabrizio . The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2556.
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