| ชื่อเรื่อง | : | Biomimicking polysaccharide nanofibers promote vascular phenotypes : a potential application for vascular tissue engineering |
| นักวิจัย | : | Shi, Liya , Aid, Rachida , Visage, Catherine Le , Chew, Sing Yian |
| คำค้น | : | DRNTU::Engineering::Bioengineering |
| หน่วยงาน | : | Nanyang Technological University, Singapore |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2555 |
| อ้างอิง | : | Shi, L., Aid, R., Visage, C. L., & Chew, S. Y. (2012). Biomimicking polysaccharide nanofibers promote vascular phenotypes : A potential application for vascular tissue engineering. Macromolecular bioscience, 12(3), 395-401. , 1616-5187 , http://hdl.handle.net/10220/17323 , http://dx.doi.org/10.1002/mabi.201100336 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | Macromolecular bioscience |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | The potential of electrospun pullulan/dextran (P/D) nanofibers (average diameter = 323 nm) for vascular tissue engineering applications is explored. The mechanical properties of the nanofibers are of the same order of magnitude as that of human arteries (Young's modulus ≈0.88 MPa; tensile strength ≈0.35 MPa). It is demonstrated that the nanofiber topography enables cell adhesion and that the endothelial phenotype is maintained on the nanofibers. Moreover, P/D nanofibers support a stable confluent monolayer of endothelial cells over 14 d. SMCs seeded on nanofibers display similar levels of alpha smooth muscle actin and a lower proliferation rate than cells on 2D cultures. The observations suggest that nanofibers promote a shift to a quiescent contractile phenotype in SMCs. |
| บรรณานุกรม | : |
Shi, Liya , Aid, Rachida , Visage, Catherine Le , Chew, Sing Yian . (2555). Biomimicking polysaccharide nanofibers promote vascular phenotypes : a potential application for vascular tissue engineering.
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Shi, Liya , Aid, Rachida , Visage, Catherine Le , Chew, Sing Yian . 2555. "Biomimicking polysaccharide nanofibers promote vascular phenotypes : a potential application for vascular tissue engineering".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Shi, Liya , Aid, Rachida , Visage, Catherine Le , Chew, Sing Yian . "Biomimicking polysaccharide nanofibers promote vascular phenotypes : a potential application for vascular tissue engineering."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print. Shi, Liya , Aid, Rachida , Visage, Catherine Le , Chew, Sing Yian . Biomimicking polysaccharide nanofibers promote vascular phenotypes : a potential application for vascular tissue engineering. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.
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