| ชื่อเรื่อง | : | FUSE : a system for data-driven multi-level functional summarization of protein interaction networks |
| นักวิจัย | : | Seah, Boon-Siew , Bhowmick, Sourav S. , Dewey Jr., C. Forbes , Yu, Hanry |
| คำค้น | : | DRNTU::Engineering::Computer science and engineering::Computing methodologies::Simulation and modeling. |
| หน่วยงาน | : | Nanyang Technological University, Singapore |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2555 |
| อ้างอิง | : | Seah, B.-S., Bhowmick, S. S., Dewey, C. F., & Yu, H. (2012). FUSE : a system for data-driven multi-level functional summarization of protein interaction networks. Proceedings of the 2nd ACM SIGHIT International Health Informatics Symposium, pp847-850. , http://hdl.handle.net/10220/16669 , http://dx.doi.org/10.1145/2110363.2110470 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | - |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | Despite recent progress in high-throughput experimental studies, systems level visualization and analysis of large protein interaction networks (PPI) remains a challenging task, given its scale and high-dimensionality. Specifically, techniques that automatically abstract and summarize PPIs at multiple resolutions to provide high level views of its functional landscape are still lacking. In this demonstration, we present a novel data-driven and generic system called FUSE (Functional Summary Generator) that generates functional maps of a PPI at different levels of organization, from broad process-process level interactions to in-depth complex-complex level interactions. By simultaneously evaluating interaction and annotation data, FUSE abstracts higher-order interaction maps by reducing the details of the underlying PPI to form a functional summary graph of interconnected functional clusters. We demonstrate various innovative features of FUSE which aid users to visualize these summaries in a user-friendly manner and navigate through complex PPIs. |
| บรรณานุกรม | : |
Seah, Boon-Siew , Bhowmick, Sourav S. , Dewey Jr., C. Forbes , Yu, Hanry . (2555). FUSE : a system for data-driven multi-level functional summarization of protein interaction networks.
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Seah, Boon-Siew , Bhowmick, Sourav S. , Dewey Jr., C. Forbes , Yu, Hanry . 2555. "FUSE : a system for data-driven multi-level functional summarization of protein interaction networks".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Seah, Boon-Siew , Bhowmick, Sourav S. , Dewey Jr., C. Forbes , Yu, Hanry . "FUSE : a system for data-driven multi-level functional summarization of protein interaction networks."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print. Seah, Boon-Siew , Bhowmick, Sourav S. , Dewey Jr., C. Forbes , Yu, Hanry . FUSE : a system for data-driven multi-level functional summarization of protein interaction networks. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.
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