| ชื่อเรื่อง | : | Visualizing the high curvature regions of post-mitotic nascent nuclear envelope membrane. |
| นักวิจัย | : | Lu, Lei. , Kirchhausen, Tomas. |
| คำค้น | : | DRNTU::Science::Biological sciences. |
| หน่วยงาน | : | Nanyang Technological University, Singapore |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2554 |
| อ้างอิง | : | http://hdl.handle.net/10220/13053 , http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291306/ |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | Communicative & integrative biology |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | We previously reported that mitotic endoplasmic reticulum (ER) membrane cisternae or sheets directly assemble mammalian nuclear envelope (NE) at the end of mitosis. In this study, we investigated the dynamics of the high curvature regions of partially assembled nuclear envelope membrane using reticulon4a as a probe. We found that, after sorting out reticulon4a from the nascent NE membrane sheets, reticulon4a is specifically localized to the leading edges. Our 3D time lapse images suggested that ER tubules could be incompetent in assembling the NE membrane. Our findings suggest a possible role of reticulons at the leading edges during the NE re-assembly and provide further evidences that the mitotic assembly of NE is by ER cisternae rather than tubules. |
| บรรณานุกรม | : |
Lu, Lei. , Kirchhausen, Tomas. . (2554). Visualizing the high curvature regions of post-mitotic nascent nuclear envelope membrane..
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Lu, Lei. , Kirchhausen, Tomas. . 2554. "Visualizing the high curvature regions of post-mitotic nascent nuclear envelope membrane.".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Lu, Lei. , Kirchhausen, Tomas. . "Visualizing the high curvature regions of post-mitotic nascent nuclear envelope membrane.."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2554. Print. Lu, Lei. , Kirchhausen, Tomas. . Visualizing the high curvature regions of post-mitotic nascent nuclear envelope membrane.. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2554.
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