| ชื่อเรื่อง | : | Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment. |
| นักวิจัย | : | Wong, Clarence T. T. , Rowlands, Dewi K. , Wong, Chi-Hang. , Lo, Theodore W. C. , Nguyen, Giang K. T. , Li, Hoi-Yeung. , Tam, James P. |
| คำค้น | : | DRNTU::Science::Biological sciences. |
| หน่วยงาน | : | Nanyang Technological University, Singapore |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2555 |
| อ้างอิง | : | Wong, C. T. T., Rowlands, D. K., Wong, C.-H., Lo, T. W. C., Nguyen, G. K. T., Li, H.-Y., et al. (2012). Orally Active Peptidic Bradykinin B1 Receptor Antagonists Engineered from a Cyclotide Scaffold for Inflammatory Pain Treatment. Angewandte Chemie International Edition, 51(23), 5620-5624. , 1433-7851 , http://hdl.handle.net/10220/12497 , http://dx.doi.org/10.1002/anie.201200984 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | Angewandte chemie international edition |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | Edible: By grafting natural peptide antagonists onto the cyclotide kalata B1, orally active peptides were engineered, which are potentially useful therapeutics for the treatment of inflammatory pain. For example, the entire loop 6 of kalata B1 was replaced with the peptidic bradykinin B1 receptor antagonist DALK (red in scheme) to obtain the cyclic bradykinin antagonist ckb-kal. |
| บรรณานุกรม | : |
Wong, Clarence T. T. , Rowlands, Dewi K. , Wong, Chi-Hang. , Lo, Theodore W. C. , Nguyen, Giang K. T. , Li, Hoi-Yeung. , Tam, James P. . (2555). Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment..
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Wong, Clarence T. T. , Rowlands, Dewi K. , Wong, Chi-Hang. , Lo, Theodore W. C. , Nguyen, Giang K. T. , Li, Hoi-Yeung. , Tam, James P. . 2555. "Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment.".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Wong, Clarence T. T. , Rowlands, Dewi K. , Wong, Chi-Hang. , Lo, Theodore W. C. , Nguyen, Giang K. T. , Li, Hoi-Yeung. , Tam, James P. . "Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment.."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print. Wong, Clarence T. T. , Rowlands, Dewi K. , Wong, Chi-Hang. , Lo, Theodore W. C. , Nguyen, Giang K. T. , Li, Hoi-Yeung. , Tam, James P. . Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment.. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.
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