| ชื่อเรื่อง | : | Lecture notes in computer science : multiple DNA sequence alignment using joint weight matrix |
| นักวิจัย | : | Shu, Jian Jun , Yong, Kian Yan , Chan, Weng Kong |
| คำค้น | : | DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences |
| หน่วยงาน | : | Nanyang Technological University, Singapore |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2554 |
| อ้างอิง | : | Shu, J. J., Yong, K. Y., & Chan, W. K. (2011). Lecture notes in computer science: Multiple DNA sequence alignment using joint weight matrix. International Conference on Computational Science and Its Applications (11th:2011:Santander). , http://hdl.handle.net/10220/7188 , http://dx.doi.org/10.1007/978-3-642-21931-3_51 , 161332 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | - |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | The way for performing multiple sequence alignment is based on the criterion of the maximum scored information content computed from a weight matrix, but it is possible to have two or more alignments to have the same highest score leading to ambiguities in selecting the best alignment. This paper addresses this issue by introducing the concept of joint weight matrix to eliminate the randomness in selecting the best alignment of multiple sequences. Alignments with equal scores are iteratively re-scored with joint weight matrix of increasing level (nucleotide pairs, triplets and so on) until one single best alignment is eventually found. This method can be easily implemented to algorithms using weight matrix for scoring such as those based on the widely used Gibbs sampling method. |
| บรรณานุกรม | : |
Shu, Jian Jun , Yong, Kian Yan , Chan, Weng Kong . (2554). Lecture notes in computer science : multiple DNA sequence alignment using joint weight matrix.
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Shu, Jian Jun , Yong, Kian Yan , Chan, Weng Kong . 2554. "Lecture notes in computer science : multiple DNA sequence alignment using joint weight matrix".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Shu, Jian Jun , Yong, Kian Yan , Chan, Weng Kong . "Lecture notes in computer science : multiple DNA sequence alignment using joint weight matrix."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2554. Print. Shu, Jian Jun , Yong, Kian Yan , Chan, Weng Kong . Lecture notes in computer science : multiple DNA sequence alignment using joint weight matrix. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2554.
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