| ชื่อเรื่อง | : | Baylis-Hillman reaction assisted parallel synthesis of 3, 5-disubstituted isoxazoles and their in vivo bioevaluation as antithrombotic agents |
| นักวิจัย | : | Batra, Sanjay , Roy, Amrendra K , Patra, A , Bhaduri, A P , Surin, W R , Raghavan, S A V , Sharma, P , Kapoor, Kapil , Dikshit, Madhu |
| คำค้น | : | Baylis-Hillman reaction , Isoxazolecarbaldehyde , isoxazole , nucleophilic substitution , substituted piperazine , antithrombotic activity , platelet aggregation |
| หน่วยงาน | : | - |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2547 |
| อ้างอิง | : | Bioorg. Med. Chem., 12(9), 2059-2077 , http://hdl.handle.net/123456789/34 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | CDRI Communication No. 6468 |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | The solution phase parallel synthesis involving reactions of Baylis-Hillman products of 3-substituted-5-isoxazolecarbaldehydes with nucleophiles and their in vivo antithrombotic evaluations are described along with the results of in vitro platelet aggregation inhibition assay of a few compounds. Results of the detailed evaluation of one of the compounds as an inhibitor of platelet aggregation are also presented. |
| บรรณานุกรม | : |
Batra, Sanjay , Roy, Amrendra K , Patra, A , Bhaduri, A P , Surin, W R , Raghavan, S A V , Sharma, P , Kapoor, Kapil , Dikshit, Madhu . (). Baylis-Hillman reaction assisted parallel synthesis of 3, 5-disubstituted isoxazoles and their in vivo bioevaluation as antithrombotic agents.
: . Batra, Sanjay , Roy, Amrendra K , Patra, A , Bhaduri, A P , Surin, W R , Raghavan, S A V , Sharma, P , Kapoor, Kapil , Dikshit, Madhu . . "Baylis-Hillman reaction assisted parallel synthesis of 3, 5-disubstituted isoxazoles and their in vivo bioevaluation as antithrombotic agents".
: . Batra, Sanjay , Roy, Amrendra K , Patra, A , Bhaduri, A P , Surin, W R , Raghavan, S A V , Sharma, P , Kapoor, Kapil , Dikshit, Madhu . "Baylis-Hillman reaction assisted parallel synthesis of 3, 5-disubstituted isoxazoles and their in vivo bioevaluation as antithrombotic agents."
: , . Print. Batra, Sanjay , Roy, Amrendra K , Patra, A , Bhaduri, A P , Surin, W R , Raghavan, S A V , Sharma, P , Kapoor, Kapil , Dikshit, Madhu . Baylis-Hillman reaction assisted parallel synthesis of 3, 5-disubstituted isoxazoles and their in vivo bioevaluation as antithrombotic agents. : ; .
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