| ชื่อเรื่อง | : | Iodine catalyzed one-pot synthesis of chloro-substituted linear and angular indoloquinolines and in vitro antiproliferative activity study of different indoloquinolines |
| นักวิจัย | : | Parvatkar, P.T. , Ajay, A.K. , Bhat, M.K. , Parameswaran, P.S. , Tilve, S.G. |
| คำค้น | : | Alkaloid , Antiproliferative activity , Indoloquinoline |
| หน่วยงาน | : | National Institute Of Oceanography (NIO), India |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2556 |
| อ้างอิง | : | Medicinal Chemistry Research, vol.22(1); 2013; 88–93 , http://drs.nio.org/drs/handle/2264/4423 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | - |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | This article describes a facile one-pot synthesis of different chloro-substituted linear and angular indoloquinolines using iodine as a catalyst and in vitro antiproliferative activity of these chloro-substituted indoloquinolines (3e and 3f) and some indolo[2,3-b]quinolines (3a–d) against human hepatocellular carcinoma HepG2 and human breast carcinoma MCF-7 cells. Anti-proliferative assay against human hepatocellular carcinoma HepG2 and human breast carcinoma MCF-7 cells indicated methyl-substituted 6H-indolo[2,3-b]quinoline 3c to be the most active and the parent 6H-indolo[2,3-b]quinoline 3a to be the least active, while the other compounds including the different chloro derivatives exhibited only intermediate activity. |
| บรรณานุกรม | : |
Parvatkar, P.T. , Ajay, A.K. , Bhat, M.K. , Parameswaran, P.S. , Tilve, S.G. . (2556). Iodine catalyzed one-pot synthesis of chloro-substituted linear and angular indoloquinolines and in vitro antiproliferative activity study of different indoloquinolines.
: National Institute Of Oceanography (NIO), India. Parvatkar, P.T. , Ajay, A.K. , Bhat, M.K. , Parameswaran, P.S. , Tilve, S.G. . 2556. "Iodine catalyzed one-pot synthesis of chloro-substituted linear and angular indoloquinolines and in vitro antiproliferative activity study of different indoloquinolines".
: National Institute Of Oceanography (NIO), India. Parvatkar, P.T. , Ajay, A.K. , Bhat, M.K. , Parameswaran, P.S. , Tilve, S.G. . "Iodine catalyzed one-pot synthesis of chloro-substituted linear and angular indoloquinolines and in vitro antiproliferative activity study of different indoloquinolines."
: National Institute Of Oceanography (NIO), India, 2556. Print. Parvatkar, P.T. , Ajay, A.K. , Bhat, M.K. , Parameswaran, P.S. , Tilve, S.G. . Iodine catalyzed one-pot synthesis of chloro-substituted linear and angular indoloquinolines and in vitro antiproliferative activity study of different indoloquinolines. : National Institute Of Oceanography (NIO), India; 2556.
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