| ชื่อเรื่อง | : | Aspernolides A and B, butenolides from a marine-derived fungus Aspergillus terreus |
| นักวิจัย | : | Parvatkar, R.R. , DeSouza, C. , Tripathi, A. , Naik, C.G. |
| คำค้น | : | Aspergillus terreus , Marine natural products , Butenolides , Aspernolides , Chemical extraction , Bioactive compounds |
| หน่วยงาน | : | National Institute Of Oceanography (NIO), India |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2552 |
| อ้างอิง | : | Phytochemistry, vol.70(1); 128-132 , http://drs.nio.org/drs/handle/2264/2611 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | - |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | Two aromatic butenolides, aspernolides A and B along with the known metabolites, butyrolactone I, terrein and physcion were isolated from the fermentation broth of a soft coral derived fungus Aspergillus terreus. The structures of these metabolites were assigned on the basis of detailed spectroscopic analysis. The absolute stereochemistry of aspernolides A (1) and B (2) was established by their preparation from the known butyrolactone I. Biogenetically aspernolides A and B must be derived from butyrolactone I, a well known specific inhibitor of cyclin dependent kinase (cdk) from A. terreus. When tested, aspernolide A exhibited mild cytotoxicity against cancer cell lines |
| บรรณานุกรม | : |
Parvatkar, R.R. , DeSouza, C. , Tripathi, A. , Naik, C.G. . (2552). Aspernolides A and B, butenolides from a marine-derived fungus Aspergillus terreus.
: National Institute Of Oceanography (NIO), India. Parvatkar, R.R. , DeSouza, C. , Tripathi, A. , Naik, C.G. . 2552. "Aspernolides A and B, butenolides from a marine-derived fungus Aspergillus terreus".
: National Institute Of Oceanography (NIO), India. Parvatkar, R.R. , DeSouza, C. , Tripathi, A. , Naik, C.G. . "Aspernolides A and B, butenolides from a marine-derived fungus Aspergillus terreus."
: National Institute Of Oceanography (NIO), India, 2552. Print. Parvatkar, R.R. , DeSouza, C. , Tripathi, A. , Naik, C.G. . Aspernolides A and B, butenolides from a marine-derived fungus Aspergillus terreus. : National Institute Of Oceanography (NIO), India; 2552.
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