| ชื่อเรื่อง | : | Antibacterial activity of the sponge Suberites domuncula and its primmorphs: Potential basis for epibacterial chemical defense |
| นักวิจัย | : | Thakur, N.L. , Hentschel, U. , Krasko, A. , Pabel, C.T. , Anil, A.C. , Mueller, W.E.G. |
| คำค้น | : | marine invertebrates , antibiotics , defence mechanisms , protective behaviour , bacterial diseases , proteins , cloning , metabolites , Suberites domuncula |
| หน่วยงาน | : | National Institute Of Oceanography (NIO), India |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2546 |
| อ้างอิง | : | Aquatic Microbial Ecology, Vol.31; 77-83p. , http://drs.nio.org/drs/handle/2264/1203 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | - |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | The epibacterial chemical defense of the marine sponge Suberites domuncula was explored by screening sponge extract, sponge primmorph (3-D aggregates containing proliferating cells) extract and sponge-associated as well as primmorph-associated bacteria for antibacterial activity. 16S rDNA sequencing revealed that the antimicrobially active bacteria belonged to the alpha- and gamma-subdivisions of Proteobacteria (alpha-Proteobacterium MBIC 3368, Idiomarina sp. and Pseudomonas sp., respectively). Moreover, a recombinant perforin-like protein was cloned from S. domuncula that displayed strong antibacterial activity. Based on these observations, it is proposed that the sponge may be provided with a direct (by producing antibacterial metabolites) as well as an indirect (with the help of associated bacteria) epibacterial defense. |
| บรรณานุกรม | : |
Thakur, N.L. , Hentschel, U. , Krasko, A. , Pabel, C.T. , Anil, A.C. , Mueller, W.E.G. . (2546). Antibacterial activity of the sponge Suberites domuncula and its primmorphs: Potential basis for epibacterial chemical defense.
: National Institute Of Oceanography (NIO), India. Thakur, N.L. , Hentschel, U. , Krasko, A. , Pabel, C.T. , Anil, A.C. , Mueller, W.E.G. . 2546. "Antibacterial activity of the sponge Suberites domuncula and its primmorphs: Potential basis for epibacterial chemical defense".
: National Institute Of Oceanography (NIO), India. Thakur, N.L. , Hentschel, U. , Krasko, A. , Pabel, C.T. , Anil, A.C. , Mueller, W.E.G. . "Antibacterial activity of the sponge Suberites domuncula and its primmorphs: Potential basis for epibacterial chemical defense."
: National Institute Of Oceanography (NIO), India, 2546. Print. Thakur, N.L. , Hentschel, U. , Krasko, A. , Pabel, C.T. , Anil, A.C. , Mueller, W.E.G. . Antibacterial activity of the sponge Suberites domuncula and its primmorphs: Potential basis for epibacterial chemical defense. : National Institute Of Oceanography (NIO), India; 2546.
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