| ชื่อเรื่อง | : | Herpes simplex virus type 2 acquisition among HIV-1-infected adults treated with Tenofovir disoproxyl fumarate as part of combination antiretroviral therapy: Results from the ACTG A5175 PEARLS study |
| นักวิจัย | : | Celum C. , Hong T. , Cent A. , Donnell D. , Morrow R. , Baeten J. , Firnhaber C. , Grinsztejn B. , Hosseinipour M. , Lalloo U. , Nyirenda M. , Riviere C. , Sanchez J. , Santos B. , Supparatpinyo K. , Hakim J. , Kumarasamy N. , Campbell T. |
| คำค้น | : | - |
| หน่วยงาน | : | มหาวิทยาลัยเชียงใหม่ |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2560 |
| อ้างอิง | : | 00221899 , 2-s2.0-85019691645 , 10.1093/infdis/jix029 , https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85019691645&origin=inward , http://cmuir.cmu.ac.th/jspui/handle/6653943832/40651 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | - |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. Objective: Tenofovir disoproxyl fumarate (TDF) disoproxyl fumarate (TDF) has in vitro activity against herpes simplex virus type 2 (HSV-2) and reduced HSV-2 acquisition as preexposure prophylaxis. Whether TDF-containing antiretroviral therapy (ART) reduces HSV-2 acquisition is unknown. Design: Secondary analysis of AIDS Clinical Trials Group A5175, a randomized, open-label study of 3 ART regimens among 1571 participants. Methods: HSV-2 serostatus was assessed at baseline, at study exit, and before a change in ART regimen. Results: Of 365 HSV-2-seronegative persons, 68 acquired HSV-2, with 24 receiving TDF-containing ART and 44 receiving ART without TDF (HSV-2 seroconversion incidence, 6.42 and 6.63 cases/100 person-years, respectively; hazard ratio, 0.89; 95% confidence interval,.55-1.44). Conclusions: HSV-2 acquisition was not reduced in HIVinfected, HSV-2-uninfected persons during TDF-containing ART. |
| บรรณานุกรม | : |
Celum C. , Hong T. , Cent A. , Donnell D. , Morrow R. , Baeten J. , Firnhaber C. , Grinsztejn B. , Hosseinipour M. , Lalloo U. , Nyirenda M. , Riviere C. , Sanchez J. , Santos B. , Supparatpinyo K. , Hakim J. , Kumarasamy N. , Campbell T. . (2560). Herpes simplex virus type 2 acquisition among HIV-1-infected adults treated with Tenofovir disoproxyl fumarate as part of combination antiretroviral therapy: Results from the ACTG A5175 PEARLS study.
เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ . Celum C. , Hong T. , Cent A. , Donnell D. , Morrow R. , Baeten J. , Firnhaber C. , Grinsztejn B. , Hosseinipour M. , Lalloo U. , Nyirenda M. , Riviere C. , Sanchez J. , Santos B. , Supparatpinyo K. , Hakim J. , Kumarasamy N. , Campbell T. . 2560. "Herpes simplex virus type 2 acquisition among HIV-1-infected adults treated with Tenofovir disoproxyl fumarate as part of combination antiretroviral therapy: Results from the ACTG A5175 PEARLS study".
เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ . Celum C. , Hong T. , Cent A. , Donnell D. , Morrow R. , Baeten J. , Firnhaber C. , Grinsztejn B. , Hosseinipour M. , Lalloo U. , Nyirenda M. , Riviere C. , Sanchez J. , Santos B. , Supparatpinyo K. , Hakim J. , Kumarasamy N. , Campbell T. . "Herpes simplex virus type 2 acquisition among HIV-1-infected adults treated with Tenofovir disoproxyl fumarate as part of combination antiretroviral therapy: Results from the ACTG A5175 PEARLS study."
เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ , 2560. Print. Celum C. , Hong T. , Cent A. , Donnell D. , Morrow R. , Baeten J. , Firnhaber C. , Grinsztejn B. , Hosseinipour M. , Lalloo U. , Nyirenda M. , Riviere C. , Sanchez J. , Santos B. , Supparatpinyo K. , Hakim J. , Kumarasamy N. , Campbell T. . Herpes simplex virus type 2 acquisition among HIV-1-infected adults treated with Tenofovir disoproxyl fumarate as part of combination antiretroviral therapy: Results from the ACTG A5175 PEARLS study. เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ ; 2560.
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