| ชื่อเรื่อง | : | Interspecies In Vitro Evaluation of Stereoselective Protein Binding for 3,4-Methylenedioxymethamphetamine |
| นักวิจัย | : | Wan Aasim, Wan Raihana , Soo, Choon Tan , Siew, Hua Gan |
| คำค้น | : | RS1-441 Pharmacy and materia medica |
| หน่วยงาน | : | Universiti Sains Malaysia, Malaysia |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2560 |
| อ้างอิง | : | http://eprints.usm.my/37014/1/(Interspecies_In_Vitro_Evaluation)_8103726.pdf , Wan Aasim, Wan Raihana and Soo, Choon Tan and Siew, Hua Gan (2017) Interspecies In Vitro Evaluation of Stereoselective Protein Binding for 3,4-Methylenedioxymethamphetamine. Journal of Chemistry, 2017 (810372). pp. 1-7. ISSN 2090-9063 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | https://doi.org/10.1155/2017/8103726 , http://eprints.usm.my/37014/ |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | Abuse of 3,4-methylenedioxymethamphetamine (MDMA) is becomingmore common worldwide. To date, there is no information available on stereoselectivity of MDMA protein binding in humans, rats, and mice. Since stereoselectivity plays an important role in MDMA’s pharmacokinetics and pharmacodynamics, in this study we investigated its stereoselectivity in protein binding. The stereoselective protein binding of rac-MDMA was nvestigated using two different concentrations (20 and 200 ng/mL) in human plasma and mouse and rat sera using an ultrafiltration technique. No significant stereoselectivity in protein binding was observed in both human plasma and rat serum; however, a significant stereoselective binding ( |
| บรรณานุกรม | : |
Wan Aasim, Wan Raihana , Soo, Choon Tan , Siew, Hua Gan . (2560). Interspecies In Vitro Evaluation of Stereoselective Protein
Binding for 3,4-Methylenedioxymethamphetamine.
กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia. Wan Aasim, Wan Raihana , Soo, Choon Tan , Siew, Hua Gan . 2560. "Interspecies In Vitro Evaluation of Stereoselective Protein
Binding for 3,4-Methylenedioxymethamphetamine".
กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia. Wan Aasim, Wan Raihana , Soo, Choon Tan , Siew, Hua Gan . "Interspecies In Vitro Evaluation of Stereoselective Protein
Binding for 3,4-Methylenedioxymethamphetamine."
กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia, 2560. Print. Wan Aasim, Wan Raihana , Soo, Choon Tan , Siew, Hua Gan . Interspecies In Vitro Evaluation of Stereoselective Protein
Binding for 3,4-Methylenedioxymethamphetamine. กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia; 2560.
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