Pengenalan: Kesedaran dan pengetahuan adalah aspek penting dalam program pencegahan VAP. Pengetahuan peserta kajian tentang VAP dan pencegahannya adalah sederhana. Walaubagaimanapun, pengetahuan tidak memastikan amalan mengikut garispanduan saintifik dan implementasi garispanduan memerlukan perubahan dan kelestarian. Objektif kajian: Memastikan kesan program pendidikan VAP bundle ke atas pengetahuan serta amalan jururawat dan kadar insiden serta faktor yang berkaitan dengan VAP di ICU. Introduction: Awareness and knowledge are important aspects of VAP prevention program. The participants have fair knowledge in VAP and VAP prevention. However, being knowledgeable does not assure implementation of evidence-based guideline, and guidelines adherence require the readiness to sustain that changed behavior. Study objective is to determine the effect of VAP-bundle educational program on nurses’ knowledge, practice, and incidence rate as well as factors associated with ventilator-associated pneumonia in ICU.