'Otitis media with effusion' (OME) ialah radang telinga tengah di mana terdapat koleksi cecair di telinga tengah sedangkan gegendang telinga tidak bertubang. Penyebab otitis media berkemungkinan pelbagai termasuk hipertropi adenoid, jangkitan (virus atau bacteria), alahan, alam sekitar dan faktor sosial. Hubungan antara adenoid dan OME telah lama dikaitkan tetapi mekanisma sebenar terus dibahaskan. Kami mengkaji peranan sel mas adenoid dalam penyebab OME. Otitis media with effusion (OME) is an inflammation of the middle ear in which a collection of liquid is present in the middle ear space while the tympanic membrane is intact. The pathogenesis of otitis media is multifactorial which includes factors such as adenoids hypertrophy, infection (viral or bacteria), allergy, environment and social factors. The association between adenoid and OME has long been noted but the exact mechanism is still much debated. We studied the role of adenoid mast cells in the causation of OME.