| ชื่อเรื่อง | : | High Deleterious Genomic Mutation Rate in Stationary Phase of Escherichia coli |
| นักวิจัย | : | Loewe, Laurence , Textor, Volker , Scherer, Siegfried |
| คำค้น | : | - |
| หน่วยงาน | : | Edinburgh Research Archive, United Kingdom |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2546 |
| อ้างอิง | : | Science, Vol 302, Issue 5650, 1558-1560 , 28 November 2003 , http://www.sciencemag.org/cgi/content/full/302/5650/1558 , DOI: 10.1126/science.1087911 , http://hdl.handle.net/1842/445 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | - |
| ขอบเขตของเนื้อหา | : | 3 |
| บทคัดย่อ/คำอธิบาย | : | In natural habitats, bacteria spend most of their time in some form of growth arrest. Little is known about deleterious mutations in such stages, and consequently there is limited understanding of what evolutionary events occur. In a deleterious mutation accumulation experiment in prolonged stationary phase of Escherichia coli, about 0.03 slightly deleterious mutations were observed per genome per day. This is over an order of magnitude higher than extrapolations from fast-growing cells, but in line with inferences from observations in adaptive stationary phase mutation experiments. These findings may affect understanding of bacterial evolution and the emergence of bacterial pathogenicity. |
| บรรณานุกรม | : |
Loewe, Laurence , Textor, Volker , Scherer, Siegfried . (2546). High Deleterious Genomic Mutation Rate in Stationary Phase of Escherichia coli.
กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom . Loewe, Laurence , Textor, Volker , Scherer, Siegfried . 2546. "High Deleterious Genomic Mutation Rate in Stationary Phase of Escherichia coli".
กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom . Loewe, Laurence , Textor, Volker , Scherer, Siegfried . "High Deleterious Genomic Mutation Rate in Stationary Phase of Escherichia coli."
กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom , 2546. Print. Loewe, Laurence , Textor, Volker , Scherer, Siegfried . High Deleterious Genomic Mutation Rate in Stationary Phase of Escherichia coli. กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom ; 2546.
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