| ชื่อเรื่อง | : | Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides |
| นักวิจัย | : | Choo, Joanna A. L. , Thong, Sock Yue , Yap, Jiawei , van Esch, Wim J. E. , Raida, Manfred , Meijers, Rob , Lescar, Julien , Verhelst, Steven H. L. , Grotenbreg, Gijsbert M. |
| คำค้น | : | DRNTU::Science::Biological sciences |
| หน่วยงาน | : | Nanyang Technological University, Singapore |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2557 |
| อ้างอิง | : | Choo, J. A. L., Thong, S. Y., Yap, J., van Esch, W. J. E., Raida, M., Meijers, R., et al. (2014). Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides. Angewandte chemie international edition, 53(49), 13390-13394. , 1433-7851 , http://hdl.handle.net/10220/24627 , http://dx.doi.org/10.1002/anie.201406295 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | Angewandte chemie international edition |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | Bioorthogonal cleavable linkers are attractive building blocks for compounds that can be manipulated to study biological and cellular processes. Sodium dithionite sensitive azobenzene-containing (Abc) peptides were applied for the temporary stabilization of recombinant MHC complexes, which can then be employed to generate libraries of MHC tetramers after exchange with a novel epitope. This technology represents an important tool for high-throughput studies of disease-specific T cell responses. |
| บรรณานุกรม | : |
Choo, Joanna A. L. , Thong, Sock Yue , Yap, Jiawei , van Esch, Wim J. E. , Raida, Manfred , Meijers, Rob , Lescar, Julien , Verhelst, Steven H. L. , Grotenbreg, Gijsbert M. . (2557). Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides.
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Choo, Joanna A. L. , Thong, Sock Yue , Yap, Jiawei , van Esch, Wim J. E. , Raida, Manfred , Meijers, Rob , Lescar, Julien , Verhelst, Steven H. L. , Grotenbreg, Gijsbert M. . 2557. "Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Choo, Joanna A. L. , Thong, Sock Yue , Yap, Jiawei , van Esch, Wim J. E. , Raida, Manfred , Meijers, Rob , Lescar, Julien , Verhelst, Steven H. L. , Grotenbreg, Gijsbert M. . "Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2557. Print. Choo, Joanna A. L. , Thong, Sock Yue , Yap, Jiawei , van Esch, Wim J. E. , Raida, Manfred , Meijers, Rob , Lescar, Julien , Verhelst, Steven H. L. , Grotenbreg, Gijsbert M. . Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2557.
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