Thesis (M.Sc.)--Chulalongkorn University, 2011

In this research, the method to determine ferulic acid using lab-on-paper coupled with the colorimetric detection was developed. The colorimetric reaction between ferulic acid, folin phenol reagent, and sodium carbonate solution provided the blue color. The intensity of the color depended on the concentration of ferulic acid. The limit of detection (LOD) was found to be 7.19 ppm. The limit of quantification (LOQ) was found to be 23.98 ppm. Linear region between mean intensity and the concentration of ferulic acid was observed with a good coefficient of 0.9974. To compare the determination of ferulic acid between the lab-on-paper technique and high performance liquid chromatography, the results shows that the determination of ferulic acid by lab-on-paper is simple, fast, and non-toxic. In addition, lab-on-paper was applied to detect ferulic acid in cosmetic effectively.