© 2016 Trans Tech Publications, Switzerland. In this study, the effects of heat treatment temperatures on structural and magnetic properties in MnFe 2 O 4 (MF)/SiO 2 -Na 2 O-CaO-P 2 O 5 (bioglass) bioactive glass ceramics were investigated. The MF/SiO 2 -Na 2 O-CaO-P 2 O 5 bioactive glass ceramics were fabricated under various heat treatment temperatures in a range of 600-1000°C. X-ray diffraction (XRD) technique, the scanning electron microscopy (SEM) and transmission electron microscopy (TEM) are used to characterize phase and microstructure. The magnetic properties were determined from Vibrating Sample Magnetometer (VSM). The X-ray diffraction peaks presented two major crystalline phases: MnFe 2 O 4 and Na 2 Ca 2 Si 3 O 9 . It was found that the heat treatment temperatures are the most influential parameter on microstructure and magnetic properties of the bioactive glass ceramics. The highest magnetic properties of studied ceramics were found in the sample heated at 1000°C with adding 20 wt%. MF. The microstructural properties of the studies samples were investigated and the results were then correlated with the characteristics of heat treatment temperatures as well as the microstructure of the bioactive glass ceramic.