| ชื่อเรื่อง | : | Next-generation bioinformatics analysis of bacterial genomes, with a focus on serovar host specificity and pathogenicity in Salmonella |
| นักวิจัย | : | Richardson, Emily Jane |
| คำค้น | : | Salmonella , Next-generation sequencing , Bioinformatics |
| หน่วยงาน | : | Edinburgh Research Archive, United Kingdom |
| ผู้ร่วมงาน | : | Gally, David |
| ปีพิมพ์ | : | 2556 |
| อ้างอิง | : | http://hdl.handle.net/1842/8793 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | Richardson EJ, Limaye B, Inamdar H, et al (2011) Genome sequences of Salmonella enterica serovar Typhimurium, Choleraesuis, Dublin, and Gallinarum strains of well-defined virulence in food-producing animals. J Bacteriol. 193(12):3162-3 [Genome announcement, IF: 3.726) , Richardson EJ, Watson M (2012) The automatic annotation of bacterial genomes. Briefings in Bioinformatics. doi: 10.1093/bib/bbs007 [Review, IF: 9.283] |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | Salmonella is one of the most important pathogens of mankind and animals alike, causing several billion pounds worth of damage worldwide each year. We have sequenced, annotated and published 4 genomes of Salmonella of well-defined virulence in farm animals. This provides valuable measures of intraserovar diversity and opportunities to formally link genotypes to phenotypes in target animals. Specifically, we have examined pathway detrition and mutagenesis and linked this to host specificity of the serovars. With the advent of next generation sequencing there has been a boom in genomic sequence submission, and an onslaught of -omics data has ensued. Integrating these different data types is complex and there is little available to visualise this data in the context of its genome. We present GeneBook, a web-based tool that synchronously integrates disparate datasets, displaying a fully annotated genome, enriched with publicly available data and the user's private experiments. It is accessed through a user-friendly interface that allows scientists to interrogate genomic features across multiple, heterogeneous, experiments. |
| บรรณานุกรม | : |
Richardson, Emily Jane . (2556). Next-generation bioinformatics analysis of bacterial genomes, with a focus on serovar host specificity and pathogenicity in Salmonella.
กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom . Richardson, Emily Jane . 2556. "Next-generation bioinformatics analysis of bacterial genomes, with a focus on serovar host specificity and pathogenicity in Salmonella".
กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom . Richardson, Emily Jane . "Next-generation bioinformatics analysis of bacterial genomes, with a focus on serovar host specificity and pathogenicity in Salmonella."
กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom , 2556. Print. Richardson, Emily Jane . Next-generation bioinformatics analysis of bacterial genomes, with a focus on serovar host specificity and pathogenicity in Salmonella. กรุงเทพมหานคร : Edinburgh Research Archive, United Kingdom ; 2556.
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