| ชื่อเรื่อง | : | Base mediated 7-exo-dig intramolecular cyclization of Ugi-Propargyl precursors: Ugi-Propargyl precursors and regioselective synthetic approach toward diverse 1, 4-benzoxazepine-5(2H)-ones |
| นักวิจัย | : | Pandey, Shashi , Kumar, S V , Kant, Ruchir , Chauhan, P M S |
| คำค้น | : | Base Mediated 7-Exo-Dig , Intramolecular Cyclization , Ugi-Propargyl Precursors , Ugi-Propargyl Precursors , Regioselective Synthetic Approach |
| หน่วยงาน | : | Central Drug Research Institute (CDRI), India |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2557 |
| อ้างอิง | : | Organic & Biomolecular Chemistry, 2014, 12, 5346-5350 , http://hdl.handle.net/123456789/1404 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | CSIR-CDRI Communication No. 8711 |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | A metal-free facile and efficient two-step synthetic protocol for the preparation of 1, 4-benzoxazepine-5(2H)-ones derivatives has been developed. The protocol involves Ugi reaction followed by K2CO3 mediated highly regioselective 7-exo-dig intramolecular cyclization of less-nucleophilic oxygen with the pendant alkyne moiety of Ugi-propargyl precursor to afford the 1, 4-benzoxazepine-5(2H)-one derivatives in good to excellent yields. |
| บรรณานุกรม | : |
Pandey, Shashi , Kumar, S V , Kant, Ruchir , Chauhan, P M S . (2557). Base mediated 7-exo-dig intramolecular cyclization of Ugi-Propargyl precursors: Ugi-Propargyl precursors and regioselective synthetic approach toward diverse 1, 4-benzoxazepine-5(2H)-ones.
: Central Drug Research Institute (CDRI), India. Pandey, Shashi , Kumar, S V , Kant, Ruchir , Chauhan, P M S . 2557. "Base mediated 7-exo-dig intramolecular cyclization of Ugi-Propargyl precursors: Ugi-Propargyl precursors and regioselective synthetic approach toward diverse 1, 4-benzoxazepine-5(2H)-ones".
: Central Drug Research Institute (CDRI), India. Pandey, Shashi , Kumar, S V , Kant, Ruchir , Chauhan, P M S . "Base mediated 7-exo-dig intramolecular cyclization of Ugi-Propargyl precursors: Ugi-Propargyl precursors and regioselective synthetic approach toward diverse 1, 4-benzoxazepine-5(2H)-ones."
: Central Drug Research Institute (CDRI), India, 2557. Print. Pandey, Shashi , Kumar, S V , Kant, Ruchir , Chauhan, P M S . Base mediated 7-exo-dig intramolecular cyclization of Ugi-Propargyl precursors: Ugi-Propargyl precursors and regioselective synthetic approach toward diverse 1, 4-benzoxazepine-5(2H)-ones. : Central Drug Research Institute (CDRI), India; 2557.
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