Multi-core processors represent a major evolution in computing hardware technology. Multi-core provides a network security application with more processing power from the hardware perspective. However, there are still significant software design challenges that must be overcome. In this paper, we present new architecture for multi-core supported network security applications, which aims at providing network security processing without causing performance penalty to normal network operations. We also provide an instance of this architecture – a multi-core supported intrusion detection system based on neural network. While hardware-based parallelisms have shown their advantage on throughput performance, parallelisms based multi-core provides more flexible, high performance, comprehensive, intelligent, and scalable solutions to network security applications.