| ชื่อเรื่อง | : | Biochemical and structural analysis on the molecular interaction between FK-506 binding protein (FKBP) 38 and anti-apoptotic protein BCL-2. |
| นักวิจัย | : | Kang, Congbao. |
| คำค้น | : | - |
| หน่วยงาน | : | Nanyang Technological University, Singapore |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2549 |
| อ้างอิง | : | Kang, C. B. (2006). Biochemical and structural analysis on the molecular interaction between FK-506 binding protein (FKBP) 38 and anti-apoptotic protein BCL-2. Doctoral thesis, Nanyang Technological University, Singapore. , http://hdl.handle.net/10356/6582 |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | - |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | FK506 binding protein (FKBP) 38, which is a tripartite TPR domain-containing member in the FKBP family, can help Bcl-2 localize at the mitochondrial membrane and modulate apoptosis. The regulation of Bcl-2 function by forming heterodimeric complexes with its pro-apoptotic partners is well studied. Bcl-2 is also regulated at the posttranslational level through phosphorylation of specific residues within the flexible loop. Bcl-2 contains an unusually long loop between the first and the second helices. This loop has been shown to be highly flexible based on NMR and X-ray crystallographic analyses of this region. Currently, the molecular basis of alternative regulatory mechanism of Bcl-2 remains poorly understood. |
| บรรณานุกรม | : |
Kang, Congbao. . (2549). Biochemical and structural analysis on the molecular interaction between FK-506 binding protein (FKBP) 38 and anti-apoptotic protein BCL-2..
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Kang, Congbao. . 2549. "Biochemical and structural analysis on the molecular interaction between FK-506 binding protein (FKBP) 38 and anti-apoptotic protein BCL-2.".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Kang, Congbao. . "Biochemical and structural analysis on the molecular interaction between FK-506 binding protein (FKBP) 38 and anti-apoptotic protein BCL-2.."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2549. Print. Kang, Congbao. . Biochemical and structural analysis on the molecular interaction between FK-506 binding protein (FKBP) 38 and anti-apoptotic protein BCL-2.. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2549.
|
ridm@nrct.go.th ระบบคลังข้อมูลงานวิจัยไทย รายการโปรดที่คุณเลือกไว้
