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Perylene-3-ylmethanol : fluorescent organic nanoparticles as a single-component photoresponsive nanocarrier with real-time monitoring of anticancer drug release

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Perylene-3-ylmethanol : fluorescent organic nanoparticles as a single-component photoresponsive nanocarrier with real-time monitoring of anticancer drug release
นักวิจัย : Jana, Avijit , Devi, K. Sanjana P. , Maiti, Tapas K. , Singh, N. D. Pradeep
คำค้น : DRNTU::Science::Chemistry::Organic chemistry
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2555
อ้างอิง : Jana, A., Devi, K. S. P., Maiti, T. K., & Singh, N. D. P. (2012).Perylene-3-ylmethanol: Fluorescent Organic Nanoparticles as a Single-Component Photoresponsive Nanocarrier with Real-Time Monitoring of Anticancer Drug Release. Journal of the American Chemical Society, 134 (18), 7656–7659. , 0002-7863 , http://hdl.handle.net/10220/19430 , http://dx.doi.org/10.1021/ja302482k , 172096
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Journal of the American chemical society
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

We report for the first time the use of perylene-3-ylmethanol fluorescent organic nanoparticles as a drug delivery system. In the present system, perylene-3-ylmethanol nanoparticles performed four important roles: (i) “nanocarriers” for drug delivery; (ii) “phototriggers” for the drug release; (iii) fluorescent chromophores for cell imaging; and (iv) detectors for real time-monitoring of drug release. In vitro biological studies revealed that the newly developed perylene-3-ylmethanol nanoparticles exhibit good biocompatibility and cellular uptake as well as efficient photoregulated anticancer drug release ability. Such fluorescent organic nanoparticles may open up new perspectives for designing a new class of promising photoresponsive nanocarriers for drug delivery.

บรรณานุกรม :
Jana, Avijit , Devi, K. Sanjana P. , Maiti, Tapas K. , Singh, N. D. Pradeep . (2555). Perylene-3-ylmethanol : fluorescent organic nanoparticles as a single-component photoresponsive nanocarrier with real-time monitoring of anticancer drug release.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Jana, Avijit , Devi, K. Sanjana P. , Maiti, Tapas K. , Singh, N. D. Pradeep . 2555. "Perylene-3-ylmethanol : fluorescent organic nanoparticles as a single-component photoresponsive nanocarrier with real-time monitoring of anticancer drug release".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Jana, Avijit , Devi, K. Sanjana P. , Maiti, Tapas K. , Singh, N. D. Pradeep . "Perylene-3-ylmethanol : fluorescent organic nanoparticles as a single-component photoresponsive nanocarrier with real-time monitoring of anticancer drug release."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print.
Jana, Avijit , Devi, K. Sanjana P. , Maiti, Tapas K. , Singh, N. D. Pradeep . Perylene-3-ylmethanol : fluorescent organic nanoparticles as a single-component photoresponsive nanocarrier with real-time monitoring of anticancer drug release. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.