| ชื่อเรื่อง | : | Molecular Mechanism Of Acute Phase Response : Identification Of Signal Transduction Pathways Mediating Cytokine Inhibitory Effect On Human Peroxisome Proliferator Activated Receptor Alpha (PPARa) In Liver Cells |
| นักวิจัย | : | Chew , Guat Siew |
| คำค้น | : | QH1 Natural history (General - Including nature conservation, geographical distribution) |
| หน่วยงาน | : | Universiti Sains Malaysia, Malaysia |
| ผู้ร่วมงาน | : | - |
| ปีพิมพ์ | : | 2553 |
| อ้างอิง | : | http://eprints.usm.my/41719/1/CHEW_GUAT_SIEW.pdf , Chew , Guat Siew (2010) Molecular Mechanism Of Acute Phase Response : Identification Of Signal Transduction Pathways Mediating Cytokine Inhibitory Effect On Human Peroxisome Proliferator Activated Receptor Alpha (PPARa) In Liver Cells. PhD thesis, Universiti Sains Malaysia. |
| ที่มา | : | - |
| ความเชี่ยวชาญ | : | - |
| ความสัมพันธ์ | : | http://ezproxy.usm.my/login?url=http ://ethesis.usm.my/jspui , http://eprints.usm.my/41719/ |
| ขอบเขตของเนื้อหา | : | - |
| บทคัดย่อ/คำอธิบาย | : | Cytokines, like IL-6, play an important role in triggering the acute phase response (APR) of the body to injury and inflammation. The dynamics of expression and interaction of the IL-6 signalling pathway components in the regulation of peroxisome proliferator-activated receptor alpha (PPARα) during APR remain to be properly identified. In this study, we determined that three possible potential signaling pathways, JAK-STAT, PI3K and MAPK (p38 and ERK1/2) which derived from the upstream JAK and SHP2 components of the IL-6 signalling were involved in IL-6-inhibitory effect on PPARα gene expression. |
| บรรณานุกรม | : |
Chew , Guat Siew . (2553). Molecular Mechanism Of Acute Phase Response : Identification Of Signal Transduction Pathways Mediating Cytokine Inhibitory Effect On Human Peroxisome Proliferator Activated Receptor Alpha (PPARa) In Liver Cells.
กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia. Chew , Guat Siew . 2553. "Molecular Mechanism Of Acute Phase Response : Identification Of Signal Transduction Pathways Mediating Cytokine Inhibitory Effect On Human Peroxisome Proliferator Activated Receptor Alpha (PPARa) In Liver Cells".
กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia. Chew , Guat Siew . "Molecular Mechanism Of Acute Phase Response : Identification Of Signal Transduction Pathways Mediating Cytokine Inhibitory Effect On Human Peroxisome Proliferator Activated Receptor Alpha (PPARa) In Liver Cells."
กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia, 2553. Print. Chew , Guat Siew . Molecular Mechanism Of Acute Phase Response : Identification Of Signal Transduction Pathways Mediating Cytokine Inhibitory Effect On Human Peroxisome Proliferator Activated Receptor Alpha (PPARa) In Liver Cells. กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia; 2553.
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